New review provides excellent insights into why COVID vaccines harm people

Our knowledge and insights can always be expanded

Here is the title of a new medical review written by experts from a number of countries:

Autoimmune Inflammatory Reactions Triggered by the
COVID-19 Genetic Vaccines in Terminally Differentiated
Tissues

Here is the abstract and some excerpts:

“Abstract: As a result of the spread of SARS-CoV-2, a global pandemic was declared. Indiscriminate COVID-19 vaccination has been extended to include age groups and naturally immune people with minimal danger of suffering serious complications due to COVID-19. Solid immuno-histopathological evidence demonstrates that the COVID-19 genetic vaccines can display an off-target distribution in tissues that are terminally differentiated, triggering autoimmune reactions. These include the
heart and brain, which may incur in situ production of spike protein eliciting a strong autoimmunological inflammatory response. Due to the fact that every human cell which synthesizes non-self antigens becomes inevitably the target of the immune system, and since the human body is not a strictly compartmentalized system, accurate pharmacokinetic and pharmacodynamic studies are needed in order to determine precisely which tissues can be harmed. Therefore, our article aims to
draw the attention of the scientific and regulatory communities on the critical need of bio-distribution studies for the genetic vaccines against COVID-19, as well as of rational harm-benefit assessments by age group.”

Comments by Dr.Peter A. McCullough, one of the authors:

“The human immune system is designed to recognize foreign invaders (microbes, other substances) attack, kill, and then clear the debris away. For that reason, we must be sure that our bodies recognize our own cells as “protected” and the foreign ones as targets. For the first time, mRNA (Pfizer, Moderna) and adenoviral DNA (Janssen) COVID-19 vaccines install the genetic code for our bodies to make a deadly foreign protein with the aspiration that our immune system would not only respond and protect us, but also form live saving immunity from SARS-CoV-2. We have come to learn this was the drug development miscalculation of all time. Production of a foreign protein in the human body has turned out to be a disaster as illustrated by Polykretis et al in a recent paper. Here are some of the reasons why: 1) each cell that takes up the vaccine expresses the protein in the cell surface initiating autoimmune attack, 2) the tissue distribution appears to be wide involving organs where this attack could be lethal (heart, brain, bone marrow, etc.), 3) both the genetic material and the Spike protein are long lasting (months to years) which is long enough to cause an autoimmune syndrome which may be permanent.”

“Despite having a long development pathway driven by the US Military DARPA in the ADEPT P3 Program announced in 2012, genetic vaccines have been poorly conceived by contractors without careful consideration of the biological ramifications of autoimmunity. To make matters worse, they were rushed through human clinical development by Operation Warp Speed and were too widely deployed, with 92% of the US population injected at least once according to the CDC. As a result, we have nearly the entire US population at risk for or with some subclinical manifestation of autoimmunity.”

Polykretis, the lead author, elaborates: “ Strong histological evidence from biopsies and autopsies have demonstrated that the vaccine-derived spike protein was synthesized in terminally differentiated tissues (Baumeier et al., 2022; Schwab et al., 2022; Mörz, 2022). Baumeier et al. detected the vaccine-derived spike protein on the cardiomyocytes of 9 out of 15 patients with clinical suspicion of myocarditis (which were negatively tested for SARS-CoV-2), proving that the viral protein has been synthesized in the heart tissue and suggesting an autoimmune response due to vaccination (Baumeier et al., 2022). Schwab et al. describe the histopathological findings from standardized autopsies performed on 25 people who had passed away unexpectedly and within 20 days from vaccination (none of the deceased persons had SARS-CoV-2 infection prior to vaccination) (Schwab et al., 2022). Both the aforementioned studies support the idea that vaccine-induced myocardial inflammation was a consequence of excessive T-lymphocytic infiltration, predominantly CD4+ T-cells, which are the main drivers of autoimmunological myocardial injury. Mörz described the expression of the vaccine-derived spike protein in the brain and the heart of a patient who developed multifocal necrotizing encephalitis upon vaccination with BNT162b2 (Mörz, 2022). Immunohistochemistry also revealed the expression of the vaccine-encoded spike protein in the vesicular keratinocytes and the endothelial cells in the dermis (Yamamoto et al., 2022).”

“Conclusions
Numerous studies report the onset of autoimmune reactions following COVID-19
vaccination (Gadi et al., 2021; Watad et al., 2021; Bril et al., 2021; Portuguese et al., 2021; Ghielmetti et al., 2021; Vuille-Lessard et al., 2021; Chamling et al., 2021; Clayton-Chubb et al., 2021; Minocha et al., 2021; Elrashdy et al., 2021; Garrido et al., 2021; Chen et al., 2022; Fatima et al., 2022; Mahroum et al., 2022; Finsterer, 2022; Garg & Paliwal, 2022; Kaulen et al., 2022; Kwon & Kim, 2022; Ruggeri, Giovanellla & Campennì, 2022). The histopathological data provide indisputable evidence that demonstrates that the genetic vaccines exhibit an off-target distribution, causing the synthesis of the spike protein and thus triggering autoimmune inflammatory reactions, even in tissues which are terminally differentiated and subject to symptomatic damage (Baumeier et al., 2022; Mörz, 2022; Schwab et al.,
2022). Despite the fact that the mechanisms of the antigen processing and presentation
and the consequences for cells synthesizing viral proteins are largely known and have
been characterized for decades (Kotsias, Cebrian & Alloatti, 2019), the genetic vaccines
were rolled out in the absence of accurate bio-distribution and bio-persistence evaluations in humans, and the vast majority of the scientific community accepted that without concern. Indeed, page 20 of Pfizer's non-clinical overview submitted to FDA in 2021 stated: “no RNA or protein metabolism or excretion studies will be conducted” (“BNT162b2 Module 2.4. Nonclinical Overview”). Further, the question posed by VRBPAC member Dr. Jay Portnoy on June 15 th, 2022 regarding the number of cells producing spike protein, and the amount and persistence of spike protein production after mRNA dosing was dismissed as “academic” by Pfizer representative Dr. William Gruber (“Web-Conference Silver Spring, Maryland 20993,” 2022). A similar question asked by ACIP’s Dr. Pablo Sanchez on June 23 rd , 2022 was answered by the Moderna representative: “The spike protein availability, I believe, is on the order of days, but like less than a week. But I will confirm that with our
tox folks as well” (June 23, 2022 ACIP Meeting - Votes, 2022). To our knowledge, this has not been made available. Moreover, the guidance against performing autopsies, ostensibly to limit viral transmission, implemented by many countries worldwide during the pandemic, severely limited the ability to gather more clinical information regarding direct evidence of injuries in tissues which may have led to vaccine-related deaths (Salerno et al., 2020). The association of COVID-19 vaccination with the development of serious cardiovascular complications, especially amongst the younger and healthier age groups, has been widely recognized (Mansanguan et al., 2022; Yonker et al.; “Myocardial Inflammation/Myocarditis After COVID-19 mRNA Booster Vaccination. presentation at ESC Congress 2022”). In a growing number of studies, it has been determined upon autopsy that vaccine-induced conditions were the cause of death (Choi et al., 2021; Schwab et al., 2022). In general, the potential risks of genetic vaccines that induce human cells to become targets for autoimmune attack cannot be fully assessed, without knowing the exact distribution and kinetics of LNPs and
mRNA, as well as the production and pharmacokinetics of the spike protein. Since the
human body is not a strictly compartmentalized system, this is a matter of serious concern for every current or future genetic vaccine which induces human cells to synthesize non-self antigens. In fact, for terminally differentiated tissues, the loss of cells results in irreversible damage with a potentially fatal prognosis. In conclusion, in light of the undeniable evidence of off-target distribution, the administration of genetic vaccines against COVID-19 should be halted until accurate pharmacokinetic, pharmacodynamic and genotoxicity studies are performed, or they should only be delivered in circumstances when the benefits greatly outweigh the risks.”