Your strong thesis is that the mRNA vaccines cause broad micro clots all over the body and this is contributing to many vaccine-induced cardiac events that are being blamed on "long Covid"
But outside of comments by two doctors Bakhdi and Hoffe, you do not provide any evidence this indeed is occurring. Do you have any other references documenting this occurring? Is there any paper or even published case studies in which a vaccinated person demonstrated this without having confirmed COVID-19?
You also state that only 25% of spike stays at local site and 75% spreads around the body -- do you have a reference for these numbers or is this just a guess based on your opinion? The only study I've seen is the Pfizer animal study that looked at distribution of LNPs (injected at 30x effective dose of LNP in Pfizer vaccine) and that showed the vast majority stayed local, but orders of magnitude less was measured other places in the body -- mainly the liver and local lymph nodes. Even that study didn't look at mRNA much less spike protein produced by mRNA so it doesn't tell us about whether spike protein is distributed around the body after vaccination much less in high enough quantities to produce complications.
It is an interesting hypothesis you mention that surely needs to be looked into, but your article doesn't appear to provide evidence beyond the comments of two doctors.
2. Pfizer did several studies on the bio-distribution of mRNA carrying LNP's in mice and rats. They submitted the results of the studies to the European Medicines Agency as a part of the process of approval of BNT162b2 vaccine.
Thank you for the links. The first link indeed shows the microclottong in hospitalized patients with severe Covid — what I haven’t seen is any confirmation this happened in any vaccinated people confirmed to not be recently infected.
And like you said the studies out there suggest the vast majority stays local and there is no evidence of spike protein all around the body after vaccination , much less in sufficient quantities to pose any clinical risk
The study suggested that COVID-19 infected patients produce a high amount of IgG anti-nucleocapsid SARS-CoV-2 antibody - the exact same antibody that the human body makes in response to COVID-19 vaccine.
"Scientists compared the blood samples to those from healthy controls and found the COVID-19 samples contained higher levels of the antibody IgG, which works with other immune cells, such as IgM, to respond to immune threats.
[...]IgG helps bridge a gap between innate and adaptive immune responses – a process that helps the body recognize, respond to, and remember danger. In normal cases, these features help protect the body from illness and infection. However, in some cases, this response can become hyperextended or altered and exacerbate illness. A unique finding from this study is that when researchers removed IgG from the COVID-19 blood samples, they saw molecular indicators of “blood vessel stickiness” fall. When they added these same IgG antibodies to the control samples, they saw a blood vessel inflammatory response that can lead to clotting." https://scitechdaily.com/scientists-pinpoint-rogue-antibodies-associated-with-severe-covid-19-blood-clotting/
This is interesting, and can help explain the known cytokine storm effect that characterizes severe and life-threatening COVID-19, that tends to occur when the virus is rapidly replicating out of control in the lower respiratory system where it finds the ideal environment for replication.
One could specify a hypothesis that the high levels of cAbs produced by the vaccines could contribute to some similar deleterious effect and micro-clotting, but my point is that I have not seen data demonstrating that three is a similar danger in the setting of a non-replicating vaccine -- producing a flurry of antibodies but not resulting in multiplying virus moving around the body.
It is of course possible, but important to follow up on the conjecture to verify before claiming it is true since there are many differences in a virus replicating out of control in the lower respiratory system and a flurry of antibodies elicited by non-replicating spikes produced from a vaccine injection into the deltoid muscle.
Let me know if you have seen any such studies -- I haven't but of course may have missed them if they are out there.
This is a commentary following the talking points and narratives of those claiming "spike is toxic", including flawed interpretations of VAERs and other scientifically disputed arguments this group is making.
What I am asking about is scientific studies demonstrating that indeed this purported micro-slotting occurs in vaccinated people who have not been recently infected with COVID.
This is what I found alarming if accurate. In another Substack article it was stated that a person who is infected with Covid may have 1-100 million Spike proteins in their body. As noted above, with the gene transfer therapy, jab, lethal injections etc. , there are 40 trillion mRNA molecules which manufacture many trillions more Spike proteins of which 75% enter into the circulatory system. If long haul Covid is causing micro clotting to the degree that it is, then you can imagine how much worse it will be either for someone Covid recovered and jabbed, or never infected and jabbed. As one embalmer has reported, see ST Kirsch on Rumble who interviews her, she is observing never before seen blood clots in 90% of her embalming cases who were vaccinated. If 100 million people in the world are suffering from Long Haul Covid micro clotting and their accompanying symptoms, imagine what will happen to the rest of the jabbed in the world which is about half the world's population. I know lots of jabbed people and I'm terrified what the result will be in the next 3 years. We know excess mortality is up 40-90% in the world and probably most of it is blood clotting.
Question regarding the d-dimer test: Is it used only to detect low platelets? Or can it be used to detect the particular cause of low platelets, such as the effects of the 1) Moderna covid vaccine vs. the effects of 2) chemotherapy to treat stomach cancer?
That test detects excessive blood clots, not platelets which is a separate, different blood test; neither test determines the cause of either clots or low platelets.
Why I asked (from the article): “Since early 2020, we and other researchers have pointed out that acute Covid-19 is not only a lung disease, but actually significantly affects the vascular (blood flow) and coagulation (blood clotting) systems.”
“The presence of persistent microclots and hyperactivated platelets (also involved in clotting) perpetuates coagulation and vascular pathology, resulting in cells not getting enough oxygen in the tissues to sustain bodily functions (known as cellular hypoxia). Widespread hypoxia may be central to the numerous reported debilitating symptoms.”
The D-dimer is a by-product of the blood clotting and break-down process that can be measured via analysis of a blood sample. D-dimer is released when a blood clot begins to break down. [1][2][3] More specifically, platelets in the blood are connected to a D subunit. When blood clots form, the D group between two platelets form a bond.
You ask great questions. I think we will probably have to worry about clots for a long time because they are hard to get rid of, and the spike proteins may also last a long time. As you probably know from my writings, I urge people to strengthen their immune system with vitamins D and C, quercetin and zinc; if you doctor is agreeable also think about taking daily baby dose of aspirin.
Your strong thesis is that the mRNA vaccines cause broad micro clots all over the body and this is contributing to many vaccine-induced cardiac events that are being blamed on "long Covid"
But outside of comments by two doctors Bakhdi and Hoffe, you do not provide any evidence this indeed is occurring. Do you have any other references documenting this occurring? Is there any paper or even published case studies in which a vaccinated person demonstrated this without having confirmed COVID-19?
You also state that only 25% of spike stays at local site and 75% spreads around the body -- do you have a reference for these numbers or is this just a guess based on your opinion? The only study I've seen is the Pfizer animal study that looked at distribution of LNPs (injected at 30x effective dose of LNP in Pfizer vaccine) and that showed the vast majority stayed local, but orders of magnitude less was measured other places in the body -- mainly the liver and local lymph nodes. Even that study didn't look at mRNA much less spike protein produced by mRNA so it doesn't tell us about whether spike protein is distributed around the body after vaccination much less in high enough quantities to produce complications.
It is an interesting hypothesis you mention that surely needs to be looked into, but your article doesn't appear to provide evidence beyond the comments of two doctors.
Since Joel has not responded yet I'll try to address both of your questions.
1. The latest research provides strong additional support to Dr. Bakhdi hypothesis on autoantibodies activity in forming micro blood clots.
https://scitechdaily.com/blood-clots-in-covid-19-patients-triggered-by-rogue-antibodies/
2. Pfizer did several studies on the bio-distribution of mRNA carrying LNP's in mice and rats. They submitted the results of the studies to the European Medicines Agency as a part of the process of approval of BNT162b2 vaccine.
The results could be seen in "2.3.2. Pharmacokinetics" on pp. 45-46 https://www.ema.europa.eu/en/documents/assessment-report/comirnaty-epar-public-assessment-report_en.pdf but, as you have said, nowhere does it mentions the 25%/75% LNP's distribution.
Thank you for the links. The first link indeed shows the microclottong in hospitalized patients with severe Covid — what I haven’t seen is any confirmation this happened in any vaccinated people confirmed to not be recently infected.
And like you said the studies out there suggest the vast majority stays local and there is no evidence of spike protein all around the body after vaccination , much less in sufficient quantities to pose any clinical risk
The study suggested that COVID-19 infected patients produce a high amount of IgG anti-nucleocapsid SARS-CoV-2 antibody - the exact same antibody that the human body makes in response to COVID-19 vaccine.
"Scientists compared the blood samples to those from healthy controls and found the COVID-19 samples contained higher levels of the antibody IgG, which works with other immune cells, such as IgM, to respond to immune threats.
[...]IgG helps bridge a gap between innate and adaptive immune responses – a process that helps the body recognize, respond to, and remember danger. In normal cases, these features help protect the body from illness and infection. However, in some cases, this response can become hyperextended or altered and exacerbate illness. A unique finding from this study is that when researchers removed IgG from the COVID-19 blood samples, they saw molecular indicators of “blood vessel stickiness” fall. When they added these same IgG antibodies to the control samples, they saw a blood vessel inflammatory response that can lead to clotting." https://scitechdaily.com/scientists-pinpoint-rogue-antibodies-associated-with-severe-covid-19-blood-clotting/
This is interesting, and can help explain the known cytokine storm effect that characterizes severe and life-threatening COVID-19, that tends to occur when the virus is rapidly replicating out of control in the lower respiratory system where it finds the ideal environment for replication.
One could specify a hypothesis that the high levels of cAbs produced by the vaccines could contribute to some similar deleterious effect and micro-clotting, but my point is that I have not seen data demonstrating that three is a similar danger in the setting of a non-replicating vaccine -- producing a flurry of antibodies but not resulting in multiplying virus moving around the body.
It is of course possible, but important to follow up on the conjecture to verify before claiming it is true since there are many differences in a virus replicating out of control in the lower respiratory system and a flurry of antibodies elicited by non-replicating spikes produced from a vaccine injection into the deltoid muscle.
Let me know if you have seen any such studies -- I haven't but of course may have missed them if they are out there.
Check out this article, it analyzes some research and hypotheses on the activity of vaccine spike.
https://thepulse.one/2022/03/01/covid-vaccine-injuries-is-the-vaccine-induced-spike-protein-toxic/
This is a commentary following the talking points and narratives of those claiming "spike is toxic", including flawed interpretations of VAERs and other scientifically disputed arguments this group is making.
What I am asking about is scientific studies demonstrating that indeed this purported micro-slotting occurs in vaccinated people who have not been recently infected with COVID.
This is what I found alarming if accurate. In another Substack article it was stated that a person who is infected with Covid may have 1-100 million Spike proteins in their body. As noted above, with the gene transfer therapy, jab, lethal injections etc. , there are 40 trillion mRNA molecules which manufacture many trillions more Spike proteins of which 75% enter into the circulatory system. If long haul Covid is causing micro clotting to the degree that it is, then you can imagine how much worse it will be either for someone Covid recovered and jabbed, or never infected and jabbed. As one embalmer has reported, see ST Kirsch on Rumble who interviews her, she is observing never before seen blood clots in 90% of her embalming cases who were vaccinated. If 100 million people in the world are suffering from Long Haul Covid micro clotting and their accompanying symptoms, imagine what will happen to the rest of the jabbed in the world which is about half the world's population. I know lots of jabbed people and I'm terrified what the result will be in the next 3 years. We know excess mortality is up 40-90% in the world and probably most of it is blood clotting.
Question regarding the d-dimer test: Is it used only to detect low platelets? Or can it be used to detect the particular cause of low platelets, such as the effects of the 1) Moderna covid vaccine vs. the effects of 2) chemotherapy to treat stomach cancer?
That test detects excessive blood clots, not platelets which is a separate, different blood test; neither test determines the cause of either clots or low platelets.
Why I asked (from the article): “Since early 2020, we and other researchers have pointed out that acute Covid-19 is not only a lung disease, but actually significantly affects the vascular (blood flow) and coagulation (blood clotting) systems.”
“The presence of persistent microclots and hyperactivated platelets (also involved in clotting) perpetuates coagulation and vascular pathology, resulting in cells not getting enough oxygen in the tissues to sustain bodily functions (known as cellular hypoxia). Widespread hypoxia may be central to the numerous reported debilitating symptoms.”
also:
D Dimer - StatPearls - NCBI Bookshelf
Search domain ncbi.nlm.nih.govhttps://www.ncbi.nlm.nih.gov › books › NBK431064
The D-dimer is a by-product of the blood clotting and break-down process that can be measured via analysis of a blood sample. D-dimer is released when a blood clot begins to break down. [1][2][3] More specifically, platelets in the blood are connected to a D subunit. When blood clots form, the D group between two platelets form a bond.
You ask great questions. I think we will probably have to worry about clots for a long time because they are hard to get rid of, and the spike proteins may also last a long time. As you probably know from my writings, I urge people to strengthen their immune system with vitamins D and C, quercetin and zinc; if you doctor is agreeable also think about taking daily baby dose of aspirin.
This is what doctors are telling me: they use aspirin, plavax and eliquis.
Potent fibrinolytic enzymes like Nattokinase and Lumbrokinase could be a very powerful instruments in dissolving these blood clouts.