The first article "Rapidly Increasing Serum 25(OH)D Boosts the Immune System, against Infections—Sepsis and COVID-19", in Nutrients, is by Sunil J. Wimalwansa, MD, PhD, MBA, DSc., in New Jersey, USA. He is former Head and an Emeritus Professor of Medicine, Endocrinology & Nutrition at Robert Wood Johnson (RWJ) Medical School (now merged with Rutgers University) and RWJ University Hospital, New Brunswick, New Jersey, USA.
He was previously tenured Professor of General Medicine & Endocrinology at the University of Texas Medical Branch at Galveston (1993-2001) and earlier, Senior Lecturer/Consultant physician in Clinical Medicine, Chemical Pathology & Endocrinology at Royal Postgraduate Medical School (RPMS) & Hammersmith Hospital in London, UK (1982-1992). Resume: https://www.ama-assn.org/system/files/2019-03/bio-sketch-sunil-wimalawansa_0.pdf .
He has been researching vitamin D scientifically since 1984 and clinically since 1996
Please see this table https://vitamindstopscovid.info/00-evi/#sjw-updated-ratios which summarises the vitamin D3 supplemental intake quantity recommendations in Prof. Wimalawansa's article. These are specified as as ratios - IUs per day per kilogram body weight - with different ranges of ratios for different health conditions. For people not suffering from obesity or several other health conditions, his recommendation is for 70 to 90 IU / day / kg. For 70 kg 154 lb this is 5000 to 6300 IU/ day. However, these are approximate and it is important to choose an intake which can easily be attained with, for instance, 50,000 IU capsules every week, every ten days or in some other easy to remember pattern.
This page cites the most important research articles regarding the immune system's need for at least 50 ng/mL 25-hydroxyvitamin D and how to attain this in the long-term, and in clinical emergencies, in 4 hours, such as with (for 70 kg bw) a single oral dose of 1 mg calcifediol, which *is* 25-hydroxyvitamin D. This goes straight into the bloodstream, without the 4 or so day delay due to the liver hydroxylating vitamin D3 to 25-hydroxyvitamin D, such as with the next best method of boosting levels rapidly, which is a ca. 10 mg (400,000 IU) dose of vitamin D3.
This page and the above-mentioned article cover a lot of the same research.
The first article "Rapidly Increasing Serum 25(OH)D Boosts the Immune System, against Infections—Sepsis and COVID-19", in Nutrients, is by Sunil J. Wimalwansa, MD, PhD, MBA, DSc., in New Jersey, USA. He is former Head and an Emeritus Professor of Medicine, Endocrinology & Nutrition at Robert Wood Johnson (RWJ) Medical School (now merged with Rutgers University) and RWJ University Hospital, New Brunswick, New Jersey, USA.
He was previously tenured Professor of General Medicine & Endocrinology at the University of Texas Medical Branch at Galveston (1993-2001) and earlier, Senior Lecturer/Consultant physician in Clinical Medicine, Chemical Pathology & Endocrinology at Royal Postgraduate Medical School (RPMS) & Hammersmith Hospital in London, UK (1982-1992). Resume: https://www.ama-assn.org/system/files/2019-03/bio-sketch-sunil-wimalawansa_0.pdf .
He has been researching vitamin D scientifically since 1984 and clinically since 1996
Please see this table https://vitamindstopscovid.info/00-evi/#sjw-updated-ratios which summarises the vitamin D3 supplemental intake quantity recommendations in Prof. Wimalawansa's article. These are specified as as ratios - IUs per day per kilogram body weight - with different ranges of ratios for different health conditions. For people not suffering from obesity or several other health conditions, his recommendation is for 70 to 90 IU / day / kg. For 70 kg 154 lb this is 5000 to 6300 IU/ day. However, these are approximate and it is important to choose an intake which can easily be attained with, for instance, 50,000 IU capsules every week, every ten days or in some other easy to remember pattern.
This page cites the most important research articles regarding the immune system's need for at least 50 ng/mL 25-hydroxyvitamin D and how to attain this in the long-term, and in clinical emergencies, in 4 hours, such as with (for 70 kg bw) a single oral dose of 1 mg calcifediol, which *is* 25-hydroxyvitamin D. This goes straight into the bloodstream, without the 4 or so day delay due to the liver hydroxylating vitamin D3 to 25-hydroxyvitamin D, such as with the next best method of boosting levels rapidly, which is a ca. 10 mg (400,000 IU) dose of vitamin D3.
This page and the above-mentioned article cover a lot of the same research.
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