For more information in vitamin D and the immune system, including Quraisi et al. 2014 (50 ng/mL 25-hydroxyvitamin D needed for full innate and adaptive responses) and Chauss et al. 2021 (Th1 regulatory lymphocytes from the lungs of hospitalised COVID-19 patients were stuck in their pro-inflammatory startup program, and never transition to their anti-inflammatory shutdown program, in large part or entirely due to having insufficient 25-hydroxyvitamin D for each cell to run its autocrine - inside the cell - signaling system), see: "What every MD, immunologist, virologist and epidemiologist should know about vitamin D and the immune system": https://vitamindstopscovid.info/05-mds/ .
One would think that most doctors would have figured out long ago that the seasonality of influenza and COVID-19 is primarily due to 25-hydroxyvitamin D levels: https://nutritionmatters.substack.com/p/covid-19-seasonality-is-primarily . Most of them are more interested in vaccines and other pseudo-sophisticated treatments than in nutrition.
That last paragraph is absolutely correct. Of course it is a simple matter for almost any individual to buy and take vitamin D pills, but since so many fail to do so some promotion and giveaways would be in order. It is pretty amazing that no U S local government, nor any charitable organization, (at least to my knowledge) has undertaken this themselves.
For more information in vitamin D and the immune system, including Quraisi et al. 2014 (50 ng/mL 25-hydroxyvitamin D needed for full innate and adaptive responses) and Chauss et al. 2021 (Th1 regulatory lymphocytes from the lungs of hospitalised COVID-19 patients were stuck in their pro-inflammatory startup program, and never transition to their anti-inflammatory shutdown program, in large part or entirely due to having insufficient 25-hydroxyvitamin D for each cell to run its autocrine - inside the cell - signaling system), see: "What every MD, immunologist, virologist and epidemiologist should know about vitamin D and the immune system": https://vitamindstopscovid.info/05-mds/ .
For 4 day and 4 hour repletion of 25-hydroxyvitamin D with bolus vitamin D3 and calcifediol respectively (calcifediol _is_ 25-hydroxyvitamin D): https://nutritionmatters.substack.com/p/calcifediol-25-hydroxyvitamin-d-or .
One would think that most doctors would have figured out long ago that the seasonality of influenza and COVID-19 is primarily due to 25-hydroxyvitamin D levels: https://nutritionmatters.substack.com/p/covid-19-seasonality-is-primarily . Most of them are more interested in vaccines and other pseudo-sophisticated treatments than in nutrition.
That last paragraph is absolutely correct. Of course it is a simple matter for almost any individual to buy and take vitamin D pills, but since so many fail to do so some promotion and giveaways would be in order. It is pretty amazing that no U S local government, nor any charitable organization, (at least to my knowledge) has undertaken this themselves.
The graphs from the Israeli study are stunning.